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  • Febo-G 40mg Tablets 20's

Febo-G 40mg Tablets 20's

kes2,000
Description
Febo-G (Febuxostat) is a non-purine selective inhibitorof xanthine oxidase. Febuxostat is a potent, non-purine, selective inhibitor of xanthine oxidase (X.O) that achieves its therapeutic effect of decreasing serum uric acid by selectively inhibiting xanthine oxidase. Uric acid is the end product of purine metabolism and is generated in the cascade of hypoxanthine-xanthine-furic acid. Both steps in the transformation are catalyzed by xanthine oxidase. Febuxostat has been shown to potently inhibit both the oxidized and reduced forms of xanthine oxidase. At therapeutic concentrations febuxostat does not inhibit other enzymes involved in purine or pyrimidine metabolism, namely, guanine deaminase, hypoxanthine guanine phosphoribosyltransferase, orotate phosphoribosyltransferase, orotidine monophosphatedecarboxylase or purine nucleoside phosphorylase.
How to use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Febo G 40 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Precautions
Taking alcohol can increase your uric acid levels and hence aggravate gout. Febo-G is unsafe in pregnancy and breastfeeding. Please consult your doctor. It should also be used with caution in kidney and liver disease. Dose adjustment is recommended.