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  • Itacare 100mg Capsules 10's

Itacare 100mg Capsules 10's

Itacare is used to treat a variety of fungal infections. It belongs to a class of drugs known as azole antifungals. It works by stopping the growth of fungi. One capsule contains 100 mg itraconazole. Therapeutic indications
Itraconazole is indicated for the treatment of the following fungal infections when thought likely to be susceptible:
• Vulvovaginal candidiasis.
• Pityriasis versicolor.
• Dermatophytoses caused by organisms susceptible to itraconazole (Trichophyton spp. Microsporum spp. Epidermophyton floccosum) e.g. tinea pedis, tinea cruris, tinea corporis, tinea manuum.
• Oral candidiasis.
• Onychomycosis caused by dermatophytes and/or yeasts.
How to use
Method of administration: Itraconazole is for oral administration and must be taken immediately after a meal for maximal absorption.

Vulvovaginal candidiasis-200 mg twice daily for 1 day.
Pityriasis versicolor-200 mg once daily for 7 days.
Tinea corporis, tinea cruris-100 mg once daily for 15 days.
Tinea pedis, tinea manuum-100 mg once daily for 30 days.
Oral candidiasis-100 mg once daily for 14 days.
Onychomycosis-200 mg once daily for 3 months.
Contraindications: Itraconazole is contraindicated in patients with known hypersensitivity to the active substance or to any of the excipients listed. Co-administration of the following substances is contraindicated with Itraconazole:
- substrates metabolized via cytochrome P450 3A4, that can prolong the QT interval, such as astemizole, bepridil, cisapride, dofetilide, levacetylmethadole (levomethadyl), mizolastine, pimozide, quinidine, sertindole and terfenadine. Co-administration may result in increased plasma concentrations of these substrates, which can lead to QT prolongation and rare occurrences of torsade de pointes.
- HMG-CoA reductase inhibitors metabolized via cytochrome P450 3A4 such as atorvastatin, lovastatin and simvastatin
- triazolam and oral midazolam.